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Targetprotein phosphatase 1, catalytic subunit, alpha isoform 3
LigandBDBM41038
Substrate/Competitorn/a
Meas. Tech.Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1)
IC50 22349±n/a nM
Citation PubChem, PC Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
protein phosphatase 1, catalytic subunit, alpha isoform 3
Name:Serine/threonine protein phosphatase PP1-alpha catalytic subunit
Synonyms:PP-1A | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Type:PROTEIN
Mol. Mass.:37510.66
Organism:Homo sapiens (Human)
Description:ChEMBL_197827
Residue:330
Sequence:
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM41038
NameBDBM41038
Synonyms:(NE)-N-[3-(2-methylanilino)-4-oxo-1-naphthalenylidene]-2-thiophenesulfonamide | (NE)-N-[3-(2-methylanilino)-4-oxonaphthalen-1-ylidene]thiophene-2-sulfonamide | (NE)-N-[3-[(2-methylphenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]thiophene-2-sulfonamide | (NE)-N-[4-keto-3-(o-toluidino)-1-naphthylidene]thiophene-2-sulfonamide | MLS000536576 | SMR000151472 | cid_11834470
TypeSmall organic molecule
Emp. Form.C21H16N2O3S2
Mol. Mass.408.493
SMILESCc1ccccc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O |w:11.12,t:9|
Structure
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n/a