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Target
General amino acid permease AGP1
Ligand
BDBM41600
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits
EC50
305±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
General amino acid permease AGP1
Synonyms:
AGP1 | AGP1_YEAST | Agp1p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69674.09
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_85666113
Residue:
633
Sequence:
MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWVAIAPIGEGKLDAQAFFENYLAMPILIALYVGYKVWHKDWKLFIRADKIDLDSHRQIFDEELIKQEDEEYRERLRNGPYWKRVVAFWC
  
Inhibitor
Name:
BDBM41600
Synonyms:
3-(3-nitrophenyl)-1-phenyl-2-propyn-1-one | 3-(3-nitrophenyl)-1-phenyl-prop-2-yn-1-one | 3-(3-nitrophenyl)-1-phenylprop-2-yn-1-one | MLS000532224 | SMR000137164 | cid_1211724
Type:
Small organic molecule
Emp. Form.:
C15H9NO3
Mol. Mass.:
251.2369
SMILES:
[O-][N+](=O)c1cccc(c1)C#CC(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: