Reaction Details Report a problem with these data
Target
General amino acid permease AGP1
Ligand
BDBM61536
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits
EC50
570±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
General amino acid permease AGP1
Synonyms:
AGP1 | AGP1_YEAST | Agp1p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69674.09
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_85666113
Residue:
633
Sequence:
MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWVAIAPIGEGKLDAQAFFENYLAMPILIALYVGYKVWHKDWKLFIRADKIDLDSHRQIFDEELIKQEDEEYRERLRNGPYWKRVVAFWC
  
Inhibitor
Name:
BDBM61536
Synonyms:
2-chloranyl-4,4-dimethyl-3-oxidanylidene-N-phenyl-pentanamide | 2-chloro-3-keto-4,4-dimethyl-N-phenyl-valeramide | 2-chloro-4,4-dimethyl-3-oxo-N-phenylpentanamide | MLS000710931 | SMR000280697 | cid_3091421
Type:
Small organic molecule
Emp. Form.:
C13H16ClNO2
Mol. Mass.:
253.725
SMILES:
CC(C)(C)C(=O)C(Cl)C(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: