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Target
Serine/threonine-protein phosphatase
Ligand
BDBM58327
Substrate
n/a
Meas. Tech.
Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin
EC50
>285000±n/a nM
Citation
 PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69558.03
Organism:
Candida dubliniensis CD36
Description:
gi_223640082
Residue:
607
Sequence:
MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKYSTVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHLLSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLLYLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIMNEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTNVVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNYLDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNVCTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNPNTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLHGVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRLIRRLSQS
  
Inhibitor
Name:
BDBM58327
Synonyms:
MLS001204085 | N-[(4-Chloro-phenyl)-(8-hydroxy-quinolin-7-yl)-methyl]-butyramide | N-[(4-chlorophenyl)-(8-hydroxy-7-quinolinyl)methyl]butanamide | N-[(4-chlorophenyl)-(8-hydroxy-7-quinolyl)methyl]butyramide | N-[(4-chlorophenyl)-(8-hydroxyquinolin-7-yl)methyl]butanamide | N-[(4-chlorophenyl)-(8-oxidanylquinolin-7-yl)methyl]butanamide | SMR000516562 | cid_2876611
Type:
Small organic molecule
Emp. Form.:
C20H19ClN2O2
Mol. Mass.:
354.83
SMILES:
CCCC(=O)NC(c1ccc(Cl)cc1)c1ccc2cccnc2c1O
Structure:
Search PDB for entries with ligand similarity: