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Target
G protein-activated inward rectifier potassium channel 1
Ligand
BDBM50004233
Substrate
n/a
Meas. Tech.
Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing
EC50
1.486±n/a nM
Citation
 PubChem, PC Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing PubChem Bioassay (2010)[AID] 
Target
Name:
G protein-activated inward rectifier potassium channel 1
Synonyms:
Girk1 | KCNJ3_RAT | Kcnj3 | Kga
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56581.73
Organism:
Rattus norvegicus
Description:
gi_13928834
Residue:
501
Sequence:
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDISTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGGPTRMEGNLPAKLRKMNSDRFT
  
Inhibitor
Name:
BDBM50004233
Synonyms:
5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL123 | ELLIPTECINE | Ellipticin | Ellipticine | TCMDC-125546 | cid_3213
Type:
Small organic molecule
Emp. Form.:
C17H14N2
Mol. Mass.:
246.3065
SMILES:
Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12
Structure:
Search PDB for entries with ligand similarity: