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Target
Protein LANA1
Ligand
BDBM73837
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction
EC50
>75000±n/a nM
Citation
 PubChem, PC Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein LANA1
Synonyms:
LANA | LANA1 | LANA1_HHV8P
Type:
Enzyme Catalytic Domain
Mol. Mass.:
131093.36
Organism:
Human herpesvirus 8
Description:
Q9QR71
Residue:
1129
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
  
Inhibitor
Name:
BDBM73837
Synonyms:
4-[(E)-3-(4-tert-butylphenyl)-1-oxoprop-2-enyl]-1-piperazinecarboxylic acid ethyl ester | 4-[(E)-3-(4-tert-butylphenyl)acryloyl]piperazine-1-carboxylic acid ethyl ester | MLS001164467 | SMR000497453 | cid_895654 | ethyl 4-[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]piperazine-1-carboxylate | ethyl 4-[3-(4-tert-butylphenyl)acryloyl]-1-piperazinecarboxylate
Type:
Small organic molecule
Emp. Form.:
C20H28N2O3
Mol. Mass.:
344.4479
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(cc1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: