Reaction Details Report a problem with these data
Target
Type-1 angiotensin II receptor
Ligand
BDBM76117
Substrate
n/a
Meas. Tech.
Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor
EC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor PubChem Bioassay (2010)[AID] 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:
Protein
Mol. Mass.:
41080.75
Organism:
Homo sapiens (Human)
Description:
P30556
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
  
Inhibitor
Name:
BDBM76117
Synonyms:
2-naphthalenesulfonic acid [(Z)-[amino(pyridin-4-yl)methylidene]amino] ester | MLS000533599 | N'-[(2-naphthylsulfonyl)oxy]-4-pyridinecarboximidamide | SMR000141037 | [(Z)-[amino(pyridin-4-yl)methylidene]amino] naphthalene-2-sulfonate | [(Z)-[azanyl(pyridin-4-yl)methylidene]amino] naphthalene-2-sulfonate | cid_9551587 | naphthalene-2-sulfonic acid [(Z)-[amino(4-pyridyl)methylene]amino] ester
Type:
Small organic molecule
Emp. Form.:
C16H13N3O3S
Mol. Mass.:
327.358
SMILES:
NC(=NOS(=O)(=O)c1ccc2ccccc2c1)c1ccncc1 |w:2.2|
Structure:
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