Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM77499
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
9486±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM77499
Synonyms:
2-(2-Methoxy-phenylamino)-8-methyl-quinoline-3-carbonitrile | 2-(2-methoxyanilino)-8-methyl-3-quinolinecarbonitrile | 2-(2-methoxyanilino)-8-methylquinoline-3-carbonitrile | 2-[(2-methoxyphenyl)amino]-8-methyl-quinoline-3-carbonitrile | 8-methyl-2-(o-anisidino)quinoline-3-carbonitrile | MLS000551998 | SMR000172503 | cid_865262
Type:
Small organic molecule
Emp. Form.:
C18H15N3O
Mol. Mass.:
289.3312
SMILES:
COc1ccccc1Nc1nc2c(C)cccc2cc1C#N
Structure:
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