Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM77501
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
>85245±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM77501
Synonyms:
(5E)-2-(4-methoxyphenyl)-5-(3,4,5-trimethoxybenzylidene)-1,3-oxazol-4(5H)-one | (5E)-2-(4-methoxyphenyl)-5-(3,4,5-trimethoxybenzylidene)-2-oxazolin-4-one | (5E)-2-(4-methoxyphenyl)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-oxazol-4-one | (5E)-2-(4-methoxyphenyl)-5-[(3,4,5-trimethoxyphenyl)methylidene]-4-oxazolone | MLS000585672 | SMR000204235 | cid_12005122
Type:
Small organic molecule
Emp. Form.:
C20H19NO6
Mol. Mass.:
369.368
SMILES:
COc1ccc(cc1)C1=NC(=O)\C(O1)=C/c1cc(OC)c(OC)c(OC)c1 |t:9|
Structure:
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