Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM34740
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50
74200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM34740
Synonyms:
4-Phenyl-naphthalen-2-ol | 4-phenyl-2-naphthalenol | 4-phenyl-2-naphthol | 4-phenylnaphthalen-2-ol | MLS000591683 | SMR000218697 | cid_1833740
Type:
Small organic molecule
Emp. Form.:
C16H12O
Mol. Mass.:
220.2659
SMILES:
Oc1cc(-c2ccccc2)c2ccccc2c1
Structure:
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