Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM78193
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50
1410±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM78193
Synonyms:
2-(4-chlorophenyl)acetic acid [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] ester | MLS000563950 | SMR000176883 | [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] 2-(4-chlorophenyl)acetate | [(Z)-[1-azanyl-2-(2,4-dichlorophenyl)ethylidene]amino] 2-(4-chlorophenyl)ethanoate | cid_9594348
Type:
Small organic molecule
Emp. Form.:
C16H13Cl3N2O2
Mol. Mass.:
371.646
SMILES:
NC(Cc1ccc(Cl)cc1Cl)=NOC(=O)Cc1ccc(Cl)cc1 |w:11.12|
Structure:
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