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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM63221
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
1727±239 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM63221
Synonyms:
1-[(2-ketoindol-3-yl)amino]-3-(tetrahydrofurfuryl)thiourea | 1-[(2-oxidanylideneindol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | 1-[(2-oxo-3-indolyl)amino]-3-(2-oxolanylmethyl)thiourea | 1-[(2-oxoindol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | MLS000590727 | SMR000219204 | cid_6052520
Type:
Small organic molecule
Emp. Form.:
C14H16N4O2S
Mol. Mass.:
304.367
SMILES:
O=C1N=c2ccccc2=C1NNC(=S)NCC1CCCO1 |c:9,t:2|
Structure:
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