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Target
Perilipin-5
Ligand
BDBM79418
Substrate
n/a
Meas. Tech.
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
IC50
1123±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set) PubChem Bioassay (2011)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM79418
Synonyms:
(4Z)-3-(4-methylphenyl)-4-[(E)-3-phenylprop-2-enylidene]-1,2-oxazol-5-one | (4Z)-3-(4-methylphenyl)-4-[(E)-3-phenylprop-2-enylidene]-5-isoxazolone | (4Z)-4-[(E)-3-phenylprop-2-enylidene]-3-(p-tolyl)-2-isoxazolin-5-one | 3-(4-methylphenyl)-4-(3-phenyl-2-propen-1-ylidene)-5(4H)-isoxazolone | MLS000684313 | SMR000267897 | cid_2263521
Type:
Small organic molecule
Emp. Form.:
C19H15NO2
Mol. Mass.:
289.3279
SMILES:
Cc1ccc(cc1)C1=NOC(=O)\C1=C/C=C/c1ccccc1 |t:8|
Structure:
Search PDB for entries with ligand similarity: