Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM67819
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
>10000±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM67819
Synonyms:
2-methyl-2-propenoic acid [7-methyl-3-oxo-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] ester | 2-methylacrylic acid [3-keto-7-methyl-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] ester | MLS000519645 | SMR000130063 | [7-methyl-3-oxidanylidene-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] 2-methylprop-2-enoate | [7-methyl-3-oxo-2-(trifluoromethyl)-4H-1,4-benzoxazin-2-yl] 2-methylprop-2-enoate | cid_4030924
Type:
Small organic molecule
Emp. Form.:
C14H12F3NO4
Mol. Mass.:
315.2446
SMILES:
CC(=C)C(=O)OC1(Oc2cc(C)ccc2NC1=O)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: