Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68132
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
>10000±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68132
Synonyms:
(5-methyl-2-propan-2-yl-cyclohexyl) 2-[2-[(4-methoxyphenoxy)methyl]-3-methyl-benzimidazol-3-ium-1-yl]ethanoate;chloride | (5-methyl-2-propan-2-ylcyclohexyl) 2-[2-[(4-methoxyphenoxy)methyl]-3-methylbenzimidazol-3-ium-1-yl]acetate;chloride | 1-{2-[(2-isopropyl-5-methylcyclohexyl)oxy]-2-oxoethyl}-2-[(4-methoxyphenoxy)methyl]-3-methyl-1H-3,1-benzimidazol-3-ium | 2-[2-[(4-methoxyphenoxy)methyl]-3-methyl-1-benzimidazol-3-iumyl]acetic acid (5-methyl-2-propan-2-ylcyclohexyl) ester;chloride | 2-[2-[(4-methoxyphenoxy)methyl]-3-methyl-benzimidazol-3-ium-1-yl]acetic acid (2-isopropyl-5-methyl-cyclohexyl) ester;chloride | MLS000766719 | SMR000339615 | cid_16195070
Type:
Small organic molecule
Emp. Form.:
C28H37N2O4
Mol. Mass.:
465.6038
SMILES:
COc1ccc(OCc2n(CC(=O)OC3CC(C)CCC3C(C)C)c3ccccc3[n+]2C)cc1
Structure:
Search PDB for entries with ligand similarity: