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Target
Caspase-7
Ligand
BDBM63310
Substrate
n/a
Meas. Tech.
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
EC50
>85266±n/a nM
Citation
 PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay (2011)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM63310
Synonyms:
MLS000418008 | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-keto-chromene-3-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxidanylidene-chromene-3-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxo-1-benzopyran-3-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxochromene-3-carboxamide | SMR000264804 | cid_2395074
Type:
Small organic molecule
Emp. Form.:
C18H13NO5
Mol. Mass.:
323.2995
SMILES:
O=C(Nc1ccc2OCCOc2c1)c1coc2ccccc2c1=O
Structure:
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