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Target
Integrin alpha-L
Ligand
BDBM79615
Substrate
n/a
Meas. Tech.
Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50
29107±n/a nM
Citation
 PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay (2011)[AID] 
Target
Name:
Integrin alpha-L
Synonyms:
CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15
Type:
Enzyme Catalytic Domain
Mol. Mass.:
128317.79
Organism:
Mus musculus
Description:
P24063
Residue:
1163
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGEGDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNTYLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVMRKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVAHVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIFASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGHAVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAAGAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGAPLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVGAPLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVGAEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQFQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLISPINVSLNFSLLEEEGTPRDQKGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLSSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSCEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENSSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHNMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIVFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLIHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLAVPGEETKDMGCLEPSGRVTRTKA
  
Inhibitor
Name:
BDBM79615
Synonyms:
1-(2-methylbenzoyl)-N-(4-methyl-3-piperidin-1-ylsulfonylphenyl)piperidine-4-carboxamide | 1-(2-methylphenyl)carbonyl-N-(4-methyl-3-piperidin-1-ylsulfonyl-phenyl)piperidine-4-carboxamide | 1-[(2-methylphenyl)-oxomethyl]-N-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-4-piperidinecarboxamide | N-(4-methyl-3-piperidinosulfonyl-phenyl)-1-o-toluoyl-isonipecotamide | VU0424160-1 | cid_16277168
Type:
Small organic molecule
Emp. Form.:
C26H33N3O4S
Mol. Mass.:
483.623
SMILES:
Cc1ccccc1C(=O)N1CCC(CC1)C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCCCC1
Structure:
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