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Target
Tropomyosin alpha-1 chain
Ligand
BDBM61565
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71434±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM61565
Synonyms:
3-(2-furanylmethyl)-4-imino-5-phenyl-5H-[1]benzopyrano[2,3-d]pyrimidin-8-ol | 3-(2-furfuryl)-4-imino-5-phenyl-5H-chromeno[2,3-d]pyrimidin-8-ol | 3-(furan-2-ylmethyl)-4-imino-5-phenyl-5H-chromeno[2,3-d]pyrimidin-8-ol | 3-Furan-2-ylmethyl-4-imino-10-phenyl-3,10-dihydro-4H-9-oxa-1,3-diaza-anthracen-7-ol | 4-azanylidene-3-(furan-2-ylmethyl)-5-phenyl-5H-chromeno[2,3-d]pyrimidin-8-ol | MLS000778659 | SMR000415453 | cid_4328297
Type:
Small organic molecule
Emp. Form.:
C22H17N3O3
Mol. Mass.:
371.3887
SMILES:
Oc1ccc2C(c3ccccc3)c3c(Oc2c1)ncn(Cc1ccco1)c3=N
Structure:
Search PDB for entries with ligand similarity: