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Target
Alpha-1A adrenergic receptor
Ligand
BDBM50026777
Substrate
n/a
Ki
940±n/a nM
Comments
PDSP_20537
Citation
 U'Prichard, DC; Greenberg, DA; Snyder, SH Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors. Mol Pharmacol 13:454-73 (1977) [PubMed] 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A
Type:
Protein
Mol. Mass.:
51620.15
Organism:
Rattus norvegicus (Rat)
Description:
P43140
Residue:
466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
  
Inhibitor
Name:
BDBM50026777
Synonyms:
2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol | 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol (methoxamine) | 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol(Methoxamine) | CHEMBL524 | METHOXAMINE | Vasoxyl
Type:
Small organic molecule
Emp. Form.:
C11H17NO3
Mol. Mass.:
211.2576
SMILES:
COc1ccc(OC)c(c1)C(O)C(C)N
Structure:
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