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TargetHIV-1 protease
LigandBDBM81676
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
Ki 540±0.0 nM
Citation Chellappan, SKiran Kumar Reddy, GSAli, ANalam, MNAnjum, SGCao, HKairys, VFernandes, MXAltman, MDTidor, BRana, TMSchiffer, CAGilson, MK Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chem Biol Drug Des69:298-313 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
HIV-1 protease
Name:HIV-1 protease
Synonyms:n/a
Type:Protein
Mol. Mass.:10653.94
Organism:Human immunodeficiency virus
Description:O90783
Residue:98
Sequence:
PQVTLWQRPLVTIRVGGQLKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYD
QITVEICGHKAIGTVLVGPTPVNIIGRNLLTIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM81676
NameBDBM81676
Synonyms:CARB-KB49
TypeSmall organic molecule
Emp. Form.C22H31N3O7S
Mol. Mass.481.562
SMILESCNC(=O)CCC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(C[C@@H](C)O)S(=O)(=O)c1ccco1 |r|
Structure
n/a