Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 2
Ligand
BDBM81801
Substrate
n/a
Ki
178±n/a nM
Comments
PDSP_1111
Citation
 Shirley, JT; Cheng, JB Competition of leukotrienes and ICI-198,615 for [3H]LTD4 binding sites in guinea pig lung membranes suggests the involvement of two LTD4 receptor subtypes. J Pharmacol Exp Ther 258:531-6 (1991) [PubMed] 
Target
Name:
Cysteinyl leukotriene receptor 2
Synonyms:
CYSLT2R | Cysltr2 | Leukotriene D4 Beta | Uncharacterized protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36091.77
Organism:
GUINEA PIG
Description:
Q2NNR4
Residue:
317
Sequence:
MEPNNSSSRNCMIQESFKKEFYPVTYLVIFVWGALGNGLSIYVFLQTYKKSTSANVFMLNLAMSDLLFISTLPFRAHYYLNNSNWIFGDVPCRIMSYSLYVNMYTSIYFLTVLSVVRFLATVHPFRLLHVTSFRSAWILCGIIWIFTMASAAVLLMHGSEPKNSITTCLELDIRKVGKLKVMNHIALVVGFLLPFFTLSICYLLVIRVLLKVEIPESTLRASHRKALITIIIALITFLLCFLPYHTLRTLHLITWNKDSCGNGLHKAVVITLALAAANSCVNPFLYYFAGENFKDKLKAVFIKDHPQKAKCSFPICL
  
Inhibitor
Name:
BDBM81801
Synonyms:
CAS_5283121 | LTC4 | NSC_5283121
Type:
Small organic molecule
Emp. Form.:
C30H47N3O9S
Mol. Mass.:
625.774
SMILES:
CCCCCC=CCC=CC=CC=CC(SCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(O)CCCC(O)=O |w:5.4,8.7,10.9,12.11|
Structure:
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