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TargetGlycine
LigandBDBM16173
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_2650
Citation Garritsen, AIjzerman, APTulp, MTCragoe, EJSoudijn, W Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins. J Recept Res11:891-907 (1991) [PubMed]
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Glycine
Name:Glycine
Synonyms:Glycine amidinotransferase, mitochondrial
Type:Enzyme Catalytic Domain
Mol. Mass.:48247.66
Organism:RAT
Description:Glycine 0 RAT::P50442
Residue:423
Sequence:
MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSQNSCAAEDKATHPL
PKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHL
KKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEII
EAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAA
QGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPN
PMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSM
NVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQS
YFD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM16173
NameBDBM16173
Synonyms:3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride | 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide | Amiloride | Amipramidin | CHEMBL945
TypeSmall organic molecule
Emp. Form.C6H8ClN7O
Mol. Mass.229.627
SMILESNC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a