Reaction Details Report a problem with these data
Target
Glycine amidinotransferase, mitochondrial
Ligand
BDBM81818
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2651
Citation
 Garritsen, A; Ijzerman, AP; Tulp, MT; Cragoe, EJ; Soudijn, W Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins. J Recept Res 11:891-907 (1991) [PubMed]  Article 
Target
Name:
Glycine amidinotransferase, mitochondrial
Synonyms:
Agat | GATM_RAT | Gatm | Glycine | Glycine amidinotransferase, mitochondrial
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48247.66
Organism:
RAT
Description:
Glycine 0 RAT::P50442
Residue:
423
Sequence:
MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSQNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHLKKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD
  
Inhibitor
Name:
BDBM81818
Synonyms:
CAS_1794 | CHEMBL1909810 | HMA | NSC_1794
Type:
Small organic molecule
Emp. Form.:
C12H18ClN7O
Mol. Mass.:
311.771
SMILES:
NC(=N)NC(=O)c1nc(Cl)c(nc1N)N1CCCCCC1
Structure:
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