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TargetCCKBR
LigandBDBM81870
Substrate/Competitorn/a
Ki 4.9±n/a nM
CommentsPDSP_2193
Citation Lin, CWShiosaki, KMiller, TRWitte, DGBianchi, BRWolfram, CAKopecka, HCraig, RWagenaar, FNadzan, AM Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol Pharmacol39:346-51 (1991) [PubMed]
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CCKBR
Name:CCKBR
Synonyms:Cholecystokinin A
Type:Enzyme Catalytic Domain
Mol. Mass.:48683.10
Organism:GUINEA PIG
Description:Cholecystokinin A CCKBR GUINEA PIG::H0VZC5
Residue:450
Sequence:
MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNV
TSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFG
TVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSG
LLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISR
ELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPR
SRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRA
FDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARP
RPLPEEDPPTPSIASLSRLSYTTISTLGPG
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BDBM81870
NameBDBM81870
Synonyms:A-70874 | CAS_6439313 | NSC_6439313
TypeSmall organic molecule
Emp. Form.C45H55N7O10
Mol. Mass.853.9591
SMILESCNC(Cc1ccccc1)C(=O)N(C(=O)C(CC(O)=O)NC(=O)C(N)CCCCNC(=O)C=Cc1ccc(O)cc1)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C |w:32.32|
Structure
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