Reaction Details Report a problem with these data
Target
Alpha-1A adrenergic receptor
Ligand
BDBM36024
Substrate
n/a
Ki
1440±n/a nM
Comments
PDSP_1482
Citation
 Lomasney, JW; Cotecchia, S; Lorenz, W; Leung, WY; Schwinn, DA; Yang-Feng, TL; Brownstein, M; Lefkowitz, RJ; Caron, MG Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. J Biol Chem 266:6365-9 (1991) [PubMed] 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A
Type:
Protein
Mol. Mass.:
51620.15
Organism:
Rattus norvegicus (Rat)
Description:
P43140
Residue:
466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
  
Inhibitor
Name:
BDBM36024
Synonyms:
(R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephrine,(-)
Type:
Guest
Emp. Form.:
C9H14NO2
Mol. Mass.:
168.2124
SMILES:
C[NH2+]C[C@H](O)c1cccc(O)c1
Structure:
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