Target
Beta-arrestin-2
Ligand
BDBM22416
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1439
Citation
 Wong, DTThrelkeld, PGRobertson, DW Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors. Neuropsychopharmacology 5:43-7 (1991) [PubMed] 
Target
Name:
Beta-arrestin-2
Synonyms:
5-HT2C | ARRB2 | ARRB2_BOVIN | Beta-arrestin-2 | HTR2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47232.00
Organism:
Beef
Description:
5-HT2C HTR2C Beef::P32120
Residue:
420
Sequence:
MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIALPRPQSAATHPPTLLPSAVPETDAPVDTNLIEFETNYATDDDIVFEDFARLRLKGLKDEDYDDQFC
  
Inhibitor
Name:
BDBM22416
Synonyms:
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | CHEMBL490 | PAROXETINE | US09969700, Paroxetine | US9944618, Compound ID No. 182 | [3H]Paroxetine
Type:
radiolabeled ligand
Emp. Form.:
C19H20FNO3
Mol. Mass.:
329.3654
SMILES:
Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: