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Target
Protachykinin-1
Ligand
BDBM81942
Substrate
n/a
Ki
1±n/a nM
Comments
PDSP_1774
Citation
 Burcher, E; Buck, SH; Lovenberg, W; O'Donohue, TL Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J Pharmacol Exp Ther 236:819-31 (1986) [PubMed] 
Target
Name:
Protachykinin-1
Synonyms:
Nka | Nkna | Protachykinin-1 | Substance K | Substance P | TKN1_MOUSE | Tac1 | Tac2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15050.06
Organism:
MOUSE
Description:
Substance K 0 MOUSE::P41539
Residue:
130
Sequence:
MKILVAVAVFFLVSTQLFAEEIDANDDLNYWSDWSDSDQIKEAMPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSVEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRRK
  
Inhibitor
Name:
BDBM81942
Synonyms:
CAS_55582 | NKA | NSC_55582 | Neurokinin alpha | Substance K
Type:
Small organic molecule
Emp. Form.:
C50H80N14O14S
Mol. Mass.:
1133.321
SMILES:
CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc1cnc[nH]1)C(C)O)C(C)C)C(N)=O
Structure:
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