Reaction Details Report a problem with these data
Target
Substance P
Ligand
BDBM50194558
Substrate
n/a
Ki
9±n/a nM
Comments
PDSP_778
Citation
Burcher, E; Buck, SH; Lovenberg, W; O'Donohue, TL Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J Pharmacol Exp Ther 236:819-31 (1986) [PubMed]
More Info.:
Target
Name:
Substance P
Synonyms:
NKA | NKNA | TAC1 | TAC2 | TKNA_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
1350.63
Organism:
GUINEA PIG
Description:
Substance P 0 GUINEA PIG::P67932
Residue:
11
Sequence:
RPKPQQFFGLM
Inhibitor
Name:
BDBM50194558
Synonyms:
CHEMBL373569 | ELEDOISIN
Type:
Small organic molecule
Emp. Form.:
C54H85N13O15S
Mol. Mass.:
1188.396
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCC(=O)N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O