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TargetGABA A receptor alpha-3/beta-2/gamma-2
LigandBDBM81952
Substrate/Competitorn/a
Ki 205±n/a nM
CommentsPDSP_69
Citation Pritchett, DBLüddens, HSeeburg, PH Type I and type II GABAA-benzodiazepine receptors produced in transfected cells. Science245:1389-92 (1989) [PubMed]
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GABA A receptor alpha-3/beta-2/gamma-2
Name:GABA A receptor alpha-3/beta-2/gamma-2
Synonyms:GABA A Alpha3Beta3Gamma2 | GABA C | GABA receptor alpha-3 subunit | GABA-A receptor | Gamma-aminobutyric acid receptor subunit alpha-3 | agonist GABA site
Type:Enzyme Catalytic Domain
Mol. Mass.:55175.47
Organism:HUMAN
Description:GABA A Alpha3Beta1Gamma2 0 HUMAN::P34903
Residue:492
Sequence:
MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA
APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
RESAIKGMIRKQ
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  Blast E-value cutoff:
BDBM81952
NameBDBM81952
Synonyms:2-Oxoquazepam | CAS_93250 | NSC_93250
TypeSmall organic molecule
Emp. Form.C17H11ClF4N2O
Mol. Mass.370.729
SMILESFc1ccccc1C1=NCC(=O)N(CC(F)(F)F)c2ccc(Cl)cc12 |t:8|
Structure
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n/a