Reaction Details Report a problem with these data
Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50185261
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2197
Citation
 Ito, H; Sogabe, H; Nakarai, T; Sato, Y; Tomoi, M; Kadowaki, M; Matsuo, M; Tokoro, K; Yoshida, K Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide. J Pharmacol Exp Ther 268:571-5 (1994) [PubMed] 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
CCKBR | Cholecystokinin A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48683.10
Organism:
GUINEA PIG
Description:
Cholecystokinin A CCKBR GUINEA PIG::H0VZC5
Residue:
450
Sequence:
MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNVTSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISRELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPRSRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPEEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50185261
Synonyms:
4-(3,4-dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid | CHEMBL206025 | LOXIGLUMIDE
Type:
Small organic molecule
Emp. Form.:
C21H30Cl2N2O5
Mol. Mass.:
461.379
SMILES:
CCCCCN(CCCOC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: