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Target
Beta-2 adrenergic receptor
Ligand
BDBM50094670
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1142
Citation
 Foreman, MM; Fuller, RW; Rasmussen, K; Nelson, DL; Calligaro, DO; Zhang, L; Barrett, JE; Booher, RN; Paget, CJ; Flaugh, ME Pharmacological characterization of LY293284: A 5-HT1A receptor agonist with high potency and selectivity. J Pharmacol Exp Ther 270:1270-81 (1994) [PubMed] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta
Type:
PROTEIN
Mol. Mass.:
46896.26
Organism:
Rattus norvegicus
Description:
ChEMBL_38603
Residue:
418
Sequence:
MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
  
Inhibitor
Name:
BDBM50094670
Synonyms:
1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]indol-6-yl)-ethanone | CHEMBL276031 | LY 293284 | LY-293284 | LY-293384
Type:
Small organic molecule
Emp. Form.:
C19H26N2O
Mol. Mass.:
298.4225
SMILES:
CCCN(CCC)C1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23
Structure:
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