Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 6
Ligand
BDBM30701
Substrate
n/a
Ki
342±n/a nM
Comments
PDSP_1346
Citation
 Monsma, FJ; Shen, Y; Ward, RP; Hamblin, MW; Sibley, DR Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol Pharmacol 43:320-7 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_RAT | Htr6 | ST-B17 | Serotonin (5-HT) receptor | Serotonin 6 (5-HT6) receptor | Serotonin receptor 6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46945.51
Organism:
RAT
Description:
5-HT6 HTR6 RAT::P31388
Residue:
436
Sequence:
MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTPAPGQCRLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTAGQALETLQVPRTPRPGMESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVPDQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLSQTLWSLRYGRIHSVPP
  
Inhibitor
Name:
BDBM30701
Synonyms:
2-(1H-indol-3-yl)-N-methyl-ethanamine | 2-(1H-indol-3-yl)-N-methylethanamine | 2-(1H-indol-3-yl)ethyl-methyl-amine | MLS000069493 | N-OMEGA-METHYLTRYPTAMINE | N-methyltryptamine | SMR000059062 | cid_6088
Type:
Small organic molecule
Emp. Form.:
C11H14N2
Mol. Mass.:
174.2423
SMILES:
CNCCc1c[nH]c2ccccc12
Structure:
Search PDB for entries with ligand similarity: