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Reaction Details
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TargetNT
LigandBDBM50248034
Substrate/Competitorn/a
Ki 0.99±n/a nM
CommentsPDSP_1754
Citation Betancur, CCanton, MGully, DVela, GPélaprat, DRostène, W Characterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain. J Pharmacol Exp Ther273:1450-8 (1995) [PubMed]
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NT
Name:NT
Synonyms:Neurotensin
Type:Enzyme Catalytic Domain
Mol. Mass.:1681.93
Organism:GUINEA PIG
Description:NT 0 GUINEA PIG::P32560
Residue:13
Sequence:
QLYENKSRRPYIL
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BDBM50248034
NameBDBM50248034
Synonyms:2-{[1-(7-Chloro-quinolin-4-yl)-5-(2,6-dimethoxy-phenyl)-1H-pyrazole-3-carbonyl]-amino}-adamantane-2-carboxylic acid | CHEMBL506981 | SR 48692
TypeSmall organic molecule
Emp. Form.C32H31ClN4O5
Mol. Mass.587.065
SMILESCOc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)NC1(C2CC3CC(C2)CC1C3)C(O)=O |TLB:38:37:35:31.32.33,39:29:35:31.32.33,28:29:31.38.32:36.34.35,THB:38:32:29.37.36:35,39:29:31.38.32:36.34.35,28:29:35:31.32.33,33:32:29:36.34.35,33:34:29:31.38.32,(-7.63,.4,;-6.3,-.36,;-6.29,-1.9,;-7.62,-2.68,;-7.62,-4.22,;-6.29,-4.99,;-4.95,-4.22,;-3.61,-4.99,;-3.61,-6.53,;-4.95,-2.67,;-3.63,-1.9,;-2.22,-2.52,;-1.19,-1.37,;-1.97,-.04,;-3.47,-.36,;-4.62,.66,;-6.08,.17,;-7.22,1.19,;-6.91,2.71,;-5.45,3.19,;-5.14,4.69,;-3.68,5.16,;-3.37,6.67,;-2.53,4.14,;-2.85,2.64,;-4.31,2.16,;.35,-1.53,;.98,-2.93,;1.24,-.27,;2.78,-.43,;3.43,1.2,;4.84,1.23,;6.02,2.07,;5.46,3.5,;3.95,3.52,;2.87,2.58,;3.44,1.99,;4.02,.52,;5.54,.51,;3.42,-1.84,;2.51,-3.09,;4.95,-2,)|
Structure
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