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Target
Solute carrier family 22 member 1
Ligand
BDBM31046
Substrate
n/a
Ki
12.58±n/a nM
Comments
PDSP_1479
Citation
 Schwinn, DA; Johnston, GI; Page, SO; Mosley, MJ; Wilson, KH; Worman, NP; Campbell, S; Fidock, MD; Furness, LM; Parry-Smith, DJ Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. J Pharmacol Exp Ther 272:134-42 (1995) [PubMed] 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
OCT1 | S22A1_BOVIN | SLC22A1 | adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
62499.05
Organism:
BOVINE
Description:
adrenergic Alpha1 0 BOVINE::A7MBE0
Residue:
563
Sequence:
MLTVDDVLEQVGEFGWFQKQTFLILCLLSAAFAPIYVGIVFLAFTPDHRCRSPGVAELSRRCGWSLAEELNYTVPGPGPESQCLRYEVDWNQSTLGCLDPLASLATNGSPLPLGPCEQGWVYDTPGSSIVTEFNLVCDDSWKVDLFQSCVNLGFFLGSLGVGYIADRFGRKVCLLATTLTCASLGVLTAVAPDYTSLLIFRLLQGLVSKGSWTAGYTLITEFVGLGYRRTVAILYQMAFTVGLVLLSGLAYILPHWRWLQLAVSLPIFLLLFRFWFVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFIDLFRTPNLRKYTFILMYLWFTSSVVYQGLIMHVGATGGNLYLDFLYSALVEFPAGFIILVTIDRFGRRYPLATSNLAAGLACFLMIFIPHDLPWLNIMVACVGRMGITIVFQMVCLVNAELFPTFIRNLGMMVCSSLCDLGGVLTPFLVFRLMEVWQGSPLILFAALGLVAGGMTLLLPETKGVTLPETIEDAENLQRKAKPKENKIYLQVQTSELNTQAAERDASQGTAQQK
  
Inhibitor
Name:
BDBM31046
Synonyms:
3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid | 3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride | 3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid | 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid | MLS000069487 | PHENTOLAMINE | PHENTOLAMINE MESYLATE | SMR000059054 | cid_5775 | cid_91430
Type:
Small organic molecule
Emp. Form.:
C17H19N3O
Mol. Mass.:
281.3523
SMILES:
Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10|
Structure:
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