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TargetAGTR1
LigandBDBM82259
Substrate/Competitorn/a
Ki 0.7±n/a nM
CommentsPDSP_1019
Citation Keiser, JARyan, MJPanek, RLHodges, JCSircar, I Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist. J Pharmacol Exp Ther272:963-9 (1995) [PubMed]  Article
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AGTR1
Name:Angiotensin II receptor (AT-1) type-1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
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BDBM82259
NameBDBM82259
Synonyms:CAS_123856 | L-158,809 | NSC_123856
TypeSmall organic molecule
Emp. Form.C23H21N7
Mol. Mass.395.4597
SMILESCCc1nc2c(C)cc(C)nc2n1-c1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Structure
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