Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM82509
Substrate
n/a
Ki
3±n/a nM
Comments
PDSP_1197
Citation
 Reppert, SM; Weaver, DR; Ebisawa, T Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13:1177-85 (1994) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTR1A_SHEEP | Melatonin | Melatonin receptor type 1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40421.02
Organism:
Sheep
Description:
Melatonin 0 Sheep::P48040
Residue:
366
Sequence:
MAGRLWGSPGGTPKGNGSSALLNVSQAAPGAGDGVRPRPSWLAATLASILIFTIVVDIVGNLLVVLSVYRNKKLRNAGNVFVVSLAVADLLVAVYPYPLALASIVNNGWSLSSLHCQLSGFLMGLSVIGSVFSITGIAINRYCCICHSLRYGKLYSGTNSLCYVFLIWTLTLVAIVPNLCVGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMLVVVFCYLRIWALVLQVRWKVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLVVASDPASMAPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRQEYRKIIVSLCTTKMFFVDSSNHVADRIKRKPSPLIANHNLIKVDSV
  
Inhibitor
Name:
BDBM82509
Synonyms:
Melatonin,6-Hydroxy | melatonin, 6-Hydroxy
Type:
Small organic molecule
Emp. Form.:
C13H16N2O3
Mol. Mass.:
248.2777
SMILES:
COc1cc2c(CCNC(C)=O)c[nH]c2cc1O
Structure:
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