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Target
5-hydroxytryptamine receptor 3A
Ligand
BDBM81924
Substrate
n/a
Ki
2.5±n/a nM
Comments
PDSP_1522
Citation
 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH [3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus. J Pharmacol Exp Ther 267:961-70 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 3A
Synonyms:
5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_CAVPO | 5HT3R | HTR3 | HTR3A | Serotonin 3a (5-HT3a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55657.07
Organism:
GUINEA PIG
Description:
5-HT3 HTR3A GUINEA PIG::O70212
Residue:
490
Sequence:
MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA
  
Inhibitor
Name:
BDBM81924
Synonyms:
(R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-) | CAS_85976-54-1 | CHEMBL276500 | NSC_202477 | PPP, R(+)-3 | PPP, S(-)-3
Type:
Small organic molecule
Emp. Form.:
C14H21NO
Mol. Mass.:
219.3226
SMILES:
CCCN1CCCC(C1)c1cccc(O)c1
Structure:
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