Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM82518
Substrate
n/a
Ki
426.57±n/a nM
Comments
PDSP_1183
Citation
 Millan, MJ; Canton, H; Gobert, A; Lejeune, F; Rivet, JM; Bervoets, K; Brocco, M; Widdowson, P; Mennini, T; Audinot, V Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther 268:337-52 (1994) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | HTR2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51519.58
Organism:
PIG
Description:
G7ZKZ7
Residue:
457
Sequence:
MVNLRKAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAVRGPVEHSRFNSRTKAIMKIAIVWAISLGVSVPIPVIGLRDEDKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHVLRRQALMLLRGHTEEPPGISLDFLKCCKRNTDEESAANPNQDLNPRRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKVYRRAFSNYLRCNYKADKKPPIRQIPRVAATALSGRELNVNIYRHTNEPVIKKADDNEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM82518
Synonyms:
CAS_124756-23-6 | MDL 73005 EF
Type:
Small organic molecule
Emp. Form.:
C20H26N2O4
Mol. Mass.:
358.4314
SMILES:
O=C1CC2(CCCC2)CC(=O)N1CCNCC1COc2ccccc2O1
Structure:
Search PDB for entries with ligand similarity: