Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80833
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
4380±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80833
Synonyms:
Hexanoic acid [2-(4-phenyl-piperazin-1-yl)-phenyl]-amide | MLS000074446 | N-[2-(4-phenyl-1-piperazinyl)phenyl]hexanamide | N-[2-(4-phenylpiperazin-1-yl)phenyl]hexanamide | N-[2-(4-phenylpiperazino)phenyl]hexanamide | SMR000008019 | cid_650612
Type:
Small organic molecule
Emp. Form.:
C22H29N3O
Mol. Mass.:
351.4852
SMILES:
CCCCCC(=O)Nc1ccccc1N1CCN(CC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: