Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80867
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
605±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80867
Synonyms:
(4Z)-4-[[5-(3-chlorophenyl)-2-furanyl]methylidene]-2-thiophen-2-yl-5-oxazolone | (4Z)-4-[[5-(3-chlorophenyl)-2-furyl]methylene]-2-(2-thienyl)-2-oxazolin-5-one | (4Z)-4-[[5-(3-chlorophenyl)furan-2-yl]methylidene]-2-thiophen-2-yl-1,3-oxazol-5-one | 4-{[5-(3-chlorophenyl)-2-furyl]methylene}-2-(2-thienyl)-1,3-oxazol-5(4H)-one | MLS000571650 | SMR000193535 | cid_1354036
Type:
Small organic molecule
Emp. Form.:
C18H10ClNO3S
Mol. Mass.:
355.795
SMILES:
Clc1cccc(c1)-c1ccc(\C=C2/N=C(OC2=O)c2cccs2)o1 |c:14|
Structure:
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