Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM42535
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
4740±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM42535
Synonyms:
2-(4-chlorophenyl)sulfanyl-N-(2-phenylphenyl)propanamide | 2-[(4-chlorophenyl)thio]-N-(2-phenylphenyl)propanamide | 2-[(4-chlorophenyl)thio]-N-(2-phenylphenyl)propionamide | MLS000578917 | N-2-biphenylyl-2-[(4-chlorophenyl)thio]propanamide | SMR000198737 | cid_2942743
Type:
Small organic molecule
Emp. Form.:
C21H18ClNOS
Mol. Mass.:
367.892
SMILES:
CC(Sc1ccc(Cl)cc1)C(=O)Nc1ccccc1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: