Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM65601
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
3360±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM65601
Synonyms:
6-bromo-4-formyl-5-hydroxy-2-phenyl-3-benzofurancarboxylic acid ethyl ester | 6-bromo-4-formyl-5-hydroxy-2-phenyl-benzofuran-3-carboxylic acid ethyl ester | MLS001164273 | SMR000539721 | cid_1325115 | ethyl 6-bromanyl-4-methanoyl-5-oxidanyl-2-phenyl-1-benzofuran-3-carboxylate | ethyl 6-bromo-4-formyl-5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H13BrO5
Mol. Mass.:
389.197
SMILES:
CCOC(=O)c1c(oc2cc(Br)c(O)c(C=O)c12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: