Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM80753
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
7310±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM80753
Synonyms:
4-(2-hydroxy-1-naphthalenyl)naphthalene-1,2-dione | 4-(2-hydroxy-1-naphthyl)-1,2-naphthoquinone | 4-(2-hydroxynaphthalen-1-yl)naphthalene-1,2-dione | 4-(2-oxidanylnaphthalen-1-yl)naphthalene-1,2-dione | MLS002701634 | SMR001565235 | cid_265898
Type:
Small organic molecule
Emp. Form.:
C20H12O3
Mol. Mass.:
300.3075
SMILES:
Oc1ccc2ccccc2c1C1=CC(=O)C(=O)c2ccccc12 |t:13|
Structure:
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