Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM84569
Substrate
n/a
Meas. Tech.
Binding Assay
pH
7.4±0
Kd
448±13 nM
Citation
 Cochran, S; Li, CP; Bytheway, I An experimental and molecular-modeling study of the binding of linked sulfated tetracyclitols to FGF-1 and FGF-2. Chembiochem 6:1882-90 (2005) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
  
Inhibitor
Name:
BDBM84569
Synonyms:
Linked sulfated tetracyclitol, 10
Type:
Small organic molecule
Emp. Form.:
C34H44N2O48S12
Mol. Mass.:
1633.484
SMILES:
[O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCCCCCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r,c:6,35,57,79|
Structure:
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