Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 6
Ligand
BDBM81993
Substrate
n/a
Ki
125.89±n/a nM
Comments
PDSP_423
Citation
 Plassat, JL; Amlaiky, N; Hen, R Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol 44:229-36 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_MOUSE | Htr6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47012.98
Organism:
MOUSE
Description:
5-HT6 HTR6 MOUSE::Q9R1C8
Residue:
440
Sequence:
MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTSAPGQCRLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQVPRTPRPGMESADSRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHSGARPGLSLQQVLPLPLPPNSDSDSASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNFFVTDSVEPEIRQHPLGSPMN
  
Inhibitor
Name:
BDBM81993
Synonyms:
BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocriptine+ (GTP-)
Type:
n/a
Emp. Form.:
C32H40BrN5O5
Mol. Mass.:
654.594
SMILES:
CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C |r,c:28|
Structure:
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