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Target
3',5'-cyclic-AMP phosphodiesterase
Ligand
BDBM50000867
Substrate
n/a
Meas. Tech.
ChEBML_155984
EC50
520±n/a nM
Citation
 Meanwell, NA; Pearce, BC; Roth, HR; Smith, EC; Wedding, DL; Wright, JJ; Buchanan, JO; Baryla, UM; Gamberdella, M; Gillespie, E Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains. J Med Chem 35:2672-87 (1992) [PubMed]  Article 
Target
Name:
3',5'-cyclic-AMP phosphodiesterase
Synonyms:
Phosphodiesterase 4A
Type:
PROTEIN
Mol. Mass.:
13615.65
Organism:
Sus scrofa
Description:
ChEMBL_155848
Residue:
118
Sequence:
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVDIPSPTMKDHEKQQAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNEDSSIPRFGVKTDQEELLAQEL
  
Inhibitor
Name:
BDBM50000867
Synonyms:
7-(4-Hydroxy-pentyloxy)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one | CHEMBL91359
Type:
Small organic molecule
Emp. Form.:
C15H17N3O3
Mol. Mass.:
287.3138
SMILES:
CC(O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1
Structure:
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