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TargetLTB4R
LigandBDBM50001619
Substrate/Competitorn/a
Meas. Tech.ChEBML_99486
IC50 15±n/a nM
Citation Labaudinière, RHendel, WTerlain, BCavy, FMarquis, ODereu, N omega-[(4-Phenyl-2-quinolyl)oxy]alkanoic acid derivatives: a new family of potent LTB4 antagonists. J Med Chem35:4306-14 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
LTB4R
Name:Leukotriene B4 receptor
Synonyms:Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | LTB4-R 1 | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2Y purinoceptor 7 | P2Y7
Type:Enzyme Catalytic Domain
Mol. Mass.:37582.68
Organism:Homo sapiens (Human)
Description:Leukotriene B4 R1 LTB4R HUMAN::Q15722
Residue:352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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  Blast E-value cutoff:
BDBM50001619
NameBDBM50001619
Synonyms:6-[4-(4-Chloro-phenyl)-quinolin-2-yloxy]-2,2-dimethyl-hexanoic acid | CHEMBL137497
TypeSmall organic molecule
Emp. Form.C23H24ClNO3
Mol. Mass.397.895
SMILESCC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)C(O)=O
Structure
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n/a