Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50001916
Substrate
n/a
Meas. Tech.
ChEBML_37833
IC50
>100000±n/a nM
Citation
 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Synthesis, cardiac electrophysiology, and beta-blocking activity of novel arylpiperazines with potential as class II/III antiarrhythmic agents. J Med Chem 35:743-50 (1992) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50001916
Synonyms:
4-Phenyl-piperazine-2-carboxylic acid (4-methanesulfonylamino-phenyl)-amide | CHEMBL163363
Type:
Small organic molecule
Emp. Form.:
C18H22N4O3S
Mol. Mass.:
374.457
SMILES:
CS(=O)(=O)Nc1ccc(NC(=O)C2CN(CCN2)c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: