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TargetTransthyretin
LigandBDBM50241604
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1670047
Kd 1800±n/a nM
Citation Smith, TPWindsor, IWForest, KTRaines, RT Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation. J Med Chem60:7820-7834 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Transthyretin
Name:Transthyretin
Synonyms:ATTR | PALB | Prealbumin | TBPA | TTR | Transthyretin (TTR)
Type:Enzyme
Mol. Mass.:15884.31
Organism:Homo sapiens (Human)
Description:P02766
Residue:147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50241604
NameBDBM50241604
Synonyms:CHEMBL4060726
TypeSmall organic molecule
Emp. Form.C15H12O3
Mol. Mass.240.254
SMILESOC(=O)c1cccc(\C=C\c2ccc(O)cc2)c1
Structure
n/a