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Target
Thromboxane A2 receptor
Ligand
BDBM50002774
Substrate
n/a
Meas. Tech.
ChEBML_209439
Ki
18±n/a nM
Citation
 Ohshima, E; Takami, H; Sato, H; Obase, H; Miki, I; Ishii, A; Karasawa, A; Kubo, K Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1. J Med Chem 35:3394-402 (1992) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50002774
Synonyms:
11-[2-(2,3,4-Trimethoxy-benzoylamino)-ethylsulfanyl]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid | CHEMBL114785
Type:
Small organic molecule
Emp. Form.:
C27H27NO7S
Mol. Mass.:
509.571
SMILES:
COc1ccc(C(=O)NCCSC2c3ccccc3COc3ccc(cc23)C(O)=O)c(OC)c1OC
Structure:
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